Ace Therapeutics, a leading provider of preclinical research services and products, is proud to announce the launch of its extensive suite of diabetic mouse models. These models have been specifically designed to enable research on different types of diabetes including type 1, type 2, and gestational diabetes, providing valuable insights into disease mechanisms and potential treatment options.
Diabetes mellitus is a chronic, systemic, metabolic disease caused by the long-term combination of genetic factors and environmental factors, characterized by increased plasma glucose levels, mainly due to insufficient insulin secretion or dysfunction in the body (insulin resistance). Diabetes can be categorized into three primary forms – type 1, type 2, and gestational diabetes – each with distinct underlying causes. With the prevalence of diabetes increasing at an alarming rate, there is a critical need for innovative research solutions to better understand and combat this epidemic. The use of mouse models enables the study of diabetes in a way that closely mirrors the disease in humans, helping to explore disease mechanisms, find biomarkers, and evaluate potential treatments.
Mouse models provide a valuable platform for studying diabetes, mimicking human disease and aiding in research on disease mechanisms, biomarkers, and treatments. Diabetes is classified into type 1, type 2, and gestational forms. These models play a crucial role in bridging the gap between basic research and clinical application in advancing diabetes treatment and prevention.
Type 1 diabetes mouse models involve genetically modified mice that exhibit an autoimmune response leading to hyperglycemia and insulin deficiency, making them effective tools for studying disease mechanisms, biomarkers, and potential therapies.
Type 2 diabetes mouse models are created through dietary manipulation or genetic modification to induce obesity and insulin resistance, providing important insights into disease mechanisms, potential therapeutic targets, and new treatments.
Gestational diabetes mouse models are developed by feeding mice a high-fat or high-sugar diet during pregnancy or genetically altering mice to develop impaired glucose tolerance and insulin resistance during pregnancy. These models are essential for studying disease mechanisms, biomarkers, and testing potential therapies for gestational diabetes.
Ace Therapeutics provides diverse diabetic mouse models targeting type 1 diabetes mellitus (T1DM), type 2 diabetes mellitus (T2DM), and gestational diabetes mellitus (GDM). The T1DM mouse models allow researchers to study the mechanism of type 1 diabetes, identify biomarkers, and test potential therapies. Mouse models for T2DM study is generated by feeding mice a high-fat or high-sugar diet or genetically modifying mice to develop obesity and insulin resistance. These models matter a lot in type 2 diabetes research. Different from T2DM mouse models, GDM mouse models involve feeding mice a high-fat or high-sugar diet during pregnancy or genetically modifying mice to develop impaired glucose tolerance and insulin resistance during pregnancy.
“With the launch of our diabetic mouse models, we are excited to provide researchers with a reliable and versatile platform to advance their understanding of diabetes and develop novel treatments,” said the marketing manager of Ace Therapeutics. “Our models offer a high level of accuracy and reproducibility, allowing for more precise and reliable results in preclinical studies.”
Ace Therapeutics’ mouse models mimic the key characteristics of human diabetes, such as hyperglycemia, insulin resistance, and pancreatic dysfunction, making them invaluable for investigating disease pathology and testing new therapeutics. These mouse models are available for purchase immediately and can be customized to meet specific research needs as well.
About Ace Therapeutics
Ace Therapeutics is a leading provider of preclinical research products and services, specializing in drug discovery and development for metabolic disorders, infectious diseases and parasites, neurological disorders, ophthalmic diseases, gastrointestinal disorders, and immune system diseases. With a focus on innovation and quality, Ace Therapeutics is committed to supporting scientific advancements and improving human health.
